The Family and the Pharmacies begun to grow, so the sons of the Baron Francesco, the Drs Vincenzo and Giovanni, and the sons in law Dr Giovanni Canale , and Dr Tommaso Terrusi, created one of the first chains of Pharmacies in Italy.
Maria Mattera, infact, married the young Dr Giovanni Canale, who, once sold his Pharmacy on the island of Procida, begun his work in the Valley of Pompeii.
Just in Pompei, Giovanni Canale, showed all is value, and created one of the most important Pharmacies of Italy; in the 70s, 80s, and 90s, the Farmacia Canale became synonymous of honesty, professionalism, quality and class.